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| 1782 |
| | | 12-year-old Ludwig van Beethoven publishes his first composition, Piano Variations on a March by Dressler | |
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| 1783 |
| | | 20-year-old John Jacob Astor emigrates from Germany to America and sets up in the fur trade | |
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| 1787 |
| | | Mozart's opera Don Giovanni has its premiere in Prague | |
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| 1792 |
| | | Beethoven leaves Bonn and goes to Vienna to study composition with Haydn | |
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| 1793 |
| | | Russia and Prussia agree on a second partition of Poland | |
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| 1794 |
| | | Goethe and Schiller become friends, and together create the movement known as Weimar classicism | |
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| 1794 |
| | | In his Science of Knowledge Johann Gottlieb Fichte contrasts the I, or Ego, and its opposing non-I, or non-Ego | |
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| 1795 |
| | | Mungo Park sets off on his first expedition to explore the Niger on behalf of the African Association | |
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| 1796 |
| | | German physician Samuel Hahnemann coins the term 'homeopathy' and describes this new approach to medicine | |
|  | Conflict between homeopathic and allopathic medicine
Wellcome Library, London
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| 1798 |
| | | After four years in Copenhagen, German artist Caspar David Friedrich makes his life-long home in Dresden | |
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